Article:

The aim of this study was to assess the success of bone regeneration in infected and non-infected human dental defects, with respect to biological properties of bone remodeling. Histomorphometric analysis of bone biopsies was used to evaluate new bone formation, soft tissue, and residual biomaterial in infected and noninfected sites. In all samples, the biomaterial particles were surrounded by newly generated bone. Among factors that were analyzed, gender, medical state, and smoking had no significant effect on bone regeneration. Variables including tooth location, platelet concentrate, and protective membrane addition were also analyzed for their effects on bone regeneration.