Course:

The aim of the course is to explain the fundamental principles of Fibrinogen-Induced Regeneration Sealing Technique (F.I.R.S.T.), a new GBR technique that can be applied in the clinical practice after a short learning curve. 

The Fibrin Sealant (FS) is a drug of human origin used in general and specialist surgery for many decades. It is validated by over 6,000 papers in the literature. In oral surgery, FS stabilizes and maintains the natural clot for 10-14 days. It has adhesive, sealing and inductive action for hard and soft tissues formation. FS allows a better management of the particulate bone graft that, becoming plastic and adhesive, adapts perfectly to defects without shedding of granules. It also protects surgical wounds and stimulates faster soft tissue healing. The Fibrinogen-Induced Regeneration Sealing Technique (F.I.R.S.T.), invented by Foti in 2016 and published in 2020, is a GBR technique that stands out for its simplicity, predictability and low morbidity. Based on the osteoinductive and osteoconductive triad: fibrin sealant/collagenic porcine bone/collagenic porcine cortical lamina, the F.I.R.S.T. allows the reconstruction of compromised post-extraction sockets (Lamina Shield). In lateral and vertical GBR the F.I.R.S.T. is able to fix the cortical lamina for bone particles containment without tacks or screws. The outcome is a monobloc formed of cortical lamina and particulate bone graft strongly adherent to the defects, without micromovements and dead spaces, that is one of most important prerequisites for the neo-angiogenesis and the new bone formation. Furthermore, the minimally invasive “One-Time Cortical Lamina” technique, published by Foti in 2021, achieves a vestibular ridge augmen